C9H11FN2O5 Uridine, 2′ -deoxy-2′ -fluoro- (7CI, 8CI, 9CI, ACI)

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Product Detail

CAS Registry Nhamba

784-71-4

H228

Zvinhu Zvinokosha Zvemuviri	Value	Condition
Molecular Weight	246.19	-
Melting Point (Yekuedza)	149-150 °C	-
Density (zvakafanotaurwa)	1.63±0.1 g/cm3	Tembiricha: 20 °C;Dhinda: 760 Torr
pKa (Zvakafanotaurwa)	9.39±0.10	Yakanyanya Acid Temp: 25 °C

Canonical SMILES

O=C1C=CN(C(=O)N1)C2OC(CO)C(O)C2F

Isomeric SMILES

F[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C=C2

InChi

InChI= 1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4, 6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1

InChi Key

UIYWFOZZIZEEKJ-XVFCMESISA-N

4 Mamwe Mazita eChinhu ichi

2′ -Deoxy-2′ -fluorouridine (ACI);1-(2-Deoxy-2-fluoro- β -D-ribofuranosyl)uracil;2'-Fluoro-2′ -deoxyuridine;2′ -Fluoro-uridine

Properties iripo
Optical uye Kuparadzira
Thermal

Property	Value	Condition	Source
Optical Rotatory Power	+52 deg	Solvent: Mvura;λ: 589.3 nm;Tembiricha: 20 °C	(1) CAS

(1) Codington, John F.;Nyaya yeAmerican Chemical Society, (1961), 83, 5030-1, CAplus

(1) Mercer, John R.;Chinyorwa cheMedicinal Chemistry, (1989), 32 (6), 1289-94, CAplus

(2) Codington, John F.;Nyaya yeAmerican Chemical Society, (1961), 83, 5030-1, CAplus

(3) Van Aerschot, A.;Bulletin des Societes Chimiques Belges, (1989), 98(12), 937-41, CAplus

Spectra iripo
1 H NMR
13 C NMR
Hetero NMR
IR
Misa
Raman
UV uye Inooneka

Properties iripo
Biological
Chemical
Density
Lipinski
Chimiro Chinoenderana

Property	Value	Condition	Source
logP	-0.538±0.456	Tembiricha: 25 °C	(1) ACD
Mass Intrinsic Solubility	4.9 g/L	Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 1;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 2;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 3;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 4;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 5;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 6;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	pH 7;Tembiricha: 25 °C	(1) ACD
Mass Solubility	5.2 g/L	pH 8;Tembiricha: 25 °C	(1) ACD
Mass Solubility	6.9 g/L	pH 9;Tembiricha: 25 °C	(1) ACD
Mass Solubility	25 g/L	pH 10;Tembiricha: 25 °C	(1) ACD
Mass Solubility	4.9 g/L	Unbuffered Mvura pH 5.53;Tembiricha: 25 °C	(1) ACD
Molar Intrinsic Solubility	0.020 mol/L	Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 1;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 2;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 3;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 4;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 5;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 6;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	pH 7;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.021 mol/L	pH 8;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.028 mol/L	pH 9;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.10 mol/L	pH 10;Tembiricha: 25 °C	(1) ACD
Molar Solubility	0.020 mol/L	Unbuffered Mvura pH 5.53;Tembiricha: 25 °C	(1) ACD
Molecular Weight	246.19
pKa	9.39±0.10	Yakanyanya Acid Temp: 25 °C	(1) ACD

Property	Value	Condition	Source
Zvakasununguka Zvisungo Zvinotenderera	4		(1) ACD
H Vagamuchiri	7		(1) ACD
H Vanopa	3		(1) ACD
H Donor/Acceptor Sum	10		(1) ACD
logP	-0.538±0.456	Tembiricha: 25 °C	(1) ACD
Molecular Weight	246.19