Sulfamethazine
Basic Information:
Product Name: Sulfamethazine
Amweni: sulfadimethylpyrimidine
Mushonga wemakemikari: C12H14N4O2S
Structural formula:
Molecular uremu: 278.33
Nhamba yekupinda yeCAS: 57-68-1
EINECS nhamba yekupinda: 200-346-4
Zvenyama uye zvemakemikari zvinhu
Density: 1.392g/cm3
Kunyungudika: 197°C
Poindi yekubikira: 526.2ºC
Flash point: 272.1ºC
Kuonekwa: white crystalline powder
Solubility: inenge isinganyungudika mumvura, isinganyunguriki muether, inonyungudika nyore mu dilute acid kana dilute alkali solution.
Sulfadiazine mushonga we sulfanilamide une antibacterial spectrum yakafanana ne sulfadiazine. Iine antibacterial effect pa enterobacteriaceae bacteria yakadai se-non-zymogenic Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, Klebsiella, Salmonella, Shigella, etc. Neisseria gonorrhoea, Neisseria meningitidis uye Haemoenza. Zvisinei, kupikisa kwebhakitiriya kune chigadzirwa chakawedzera, kunyanya streptococcus, Neisseria uye Enterobacteriaceae mabhakitiriya. Sulfonamides i-broad-spectrum bacteriostatic agents, yakafanana muchimiro kune p-aminobenzoic acid (PABA), iyo inogona kukwikwidza kuita dihydrofolate synthetase mubhakitiriya, nokudaro ichidzivirira PABA kubva kushandiswa seyakagadziriswa kugadzira folate inodiwa nebhakitiriya uye kuderedza huwandu hwe metabolically inoshanda tetrahydrofolate. Iyo yekupedzisira chinhu chakakosha pakuumbwa kwepurines, thymidine nucleosides uye deoxyribonucleic acid (DNA), saka inotadzisa kukura uye kuberekana kwebhakitiriya.
Inonyanya kushandiswa kuhutachiona hunyoro hunokonzerwa nehutachiona hwehutachiona, hwakadai sehutachiona hwehutachiona hwehutachiona, acute otitis media uye hutachiona hweganda rakapfava.
