Praziquantel

chigadzirwa

Praziquantel

Basic Information:

Praziquantel musanganiswa wemakemikari ane chimiro chemakemikari C 19 H 24 N 2 O 2. Inonzi anthelmintic inoshandiswa muvanhu nemhuka. Inonyanya kushandiswa kurapa tapeworms uye flukes. Inonyanya kushanda pakurwisa schistosoma japonicum, Chinese chiropa fluke, uye Diphyllobothrium latum.

Mushonga wekemikari: C 19 H 24 N 2 O 2

Molecular uremu: 312.406

Nhamba yeCAS: 55268-74-1

EINECS nhamba: 259-559-6


Product Detail

Product Tags

Physicochemical pfuma

Kuwanda: 1.22 g/cm3
Kunyungudika: 136-142°C
Poindi yekuvira: 544.1°C
Painopenya: 254.6°C
Refractive index: 1.615
Kuonekwa: Ichena kana isina-white crystalline powder

use

Inonyanya kushandiswa se-broad-spectrum antiparasitic mushonga wekurapa nekudzivirira kwechikochiko, cysticercosis, paragonimiasis, echinococcosis, fasciococcus, echinococcosis, uye helminth zvirwere.

Hunhu

Ichi chigadzirwa chichena kana chisina-white crystalline powder.
Ichi chigadzirwa chinonyungudika nyore mu chloroform, chinonyungudika mu ethanol, uye chisinganyungudika mu ether kana mumvura.

Melting point

Nzvimbo yakanyungudika yechigadzirwa ichi (General Rule 0612) i136~141℃.

category

Anthelmintics.

Zviratidzo

Mushonga wakakura unorwisa trematodes uye tapeworms. Inokodzera zvakasiyana-siyana schistosomiasis, clonorchiasis, paragonimiasis, fasciolosis, tapeworm chirwere uye cysticercosis.

Pharmacological Action

Ichi chigadzirwa chinonyanya kukonzera spastic kuoma mitezo uye kudurura schistosomes uye tapeworms mune muenzi kuburikidza ne5-HT-semhedzisiro. Iine mhedzisiro yakanaka kune vakawanda vakuru uye immature tapeworms. Panguva imwecheteyo, inogona kukanganisa kukwana kwe calcium ion mumasero emuviri wehonye, ​​kuwedzera kuwanda kwe calcium ions, kurambidza kudzokororwa kwemapombi e sarcoplasmic reticulum calcium, kuwedzera zvakanyanya calcium ion zviri mukati memhasuru masero ehonye. muviri, uye kuita kuti muviri wehonye uome uye udonhe.

Storage

Ramba kure nechiedza uye chengeta mumudziyo wakavharwa.


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