isosorbide nitrate
Basic Information:
Zita remakemikari: isosorbide dinitrate; 1,4:3, 6-didehydration D-sorbitan dinitrate
Nhamba yeCAS: 87-33-2
Molecular formula: C6H8N2O8
Molecular uremu: 236.14
EINECS nhamba: 201-740-9
Mamiriro ezvinhu:
Zvikamu zvinoenderana: mbishi zvinhu; Pharmaceutical intermediates; Pharmaceutical raw materials.
Kunyungudika: 70 °C (lit.)
Poindi yekubikira: 378.59°C (yakaomarara fungidziro)
Density: 1.7503 (yakashata fungidziro)
Refractive index: 1.5010 (kufungidzira)
Flash point: 186.6±29.9 ℃
Solubility: Soluble mu chloroform, acetone, zvishoma soluble mu ethanol, zvishoma soluble mumvura.
Zvivakwa: Ichena kana chena crystalline poda, isinganhuhwi.
Mhepo yekutsikirira: 0.0±0.8 mmHg pa25℃
| tsanangudzo | unit | standard |
| Chitarisiko | Muchena kana chena crystalline poda | |
| Kuchena | % | ≥99% |
| Unyoro | % | ≤0.5 |
Isosorbide nitrate is vasodilator iyo chikuru chemishonga chiito ndechekuzorodza vascular smooth muscle. Mhedzisiro yese ndeyekudzikisa kushandiswa kweokisijeni yemhasuru yemoyo, kuwedzera kupihwa kweokisijeni, uye kubvisa angina pectoris. Clinical inogona kushandiswa kurapa marudzi akasiyana ecoronary heart disease angina pectoris uye kudzivirira kurwiswa. Intravenous drip inogona kushandiswa kurapa congestive heart failure, mhando dzakasiyana dzehypertension munguva dzekukurumidzira uye nekudzora pre-operative hypertension.
25g/ ngoma, kadhibhodhi dhiramu; Chisimbiso chekuchengetedza, yakadzika tembiricha yemhepo uye yakaoma imba yekuchengetera, isina moto, yakaparadzana chengetedzo kubva kune oxidizer.
